Senior Director, Program Manager

  • Location: Massachusetts, United States
  • Type: Direct Hire
  • Job ID: 10541
  • Work Setting: On-Site
  • Posted: August 17, 2026
  • Tax Status: W2

Perm, Senior Director, Program Manager, Biotechnology

 

Summary

Our client, a biotech start-up, has engaged GForce Life Sciences to provide a Senior Director, Program Manager. This position will report directly to the Chief Operations Officer within the C-Suite. This individual will be responsible for start-up and execution of a phase II trial.  This position requires the ability to successfully work with cross-functional teams, strong vendor management of an outsourced trial, and the ability to track overall budget and spend.

Duties / Expectations of Role

  • 10+ years of progressive, hands-on project and program management experience in biopharmaceutical drug development, spanning preclinical, clinical, regulatory, and CMC (Chemistry, Manufacturing, and Controls).
  • Demonstrated experience working with CDMOs, CROs, and other external development partners, with strong financial planning, forecasting, and budget management skills.
  • Direct experience leading cross-functional drug development programs, including regulatory filings and early-stage development activities.
  • Partner with senior leadership and key stakeholders to define program vision, asset strategy, scope, and investment requirements.
  • Lead cross-functional program teams in the development and execution of integrated project plans aligned to asset strategy.
  • Develop and maintain comprehensive, end-to-end development plans to drive a specific drug asset or portfolio through discovery, IND-enabling studies, and clinical phases.
  • Define critical paths, identify at-risk activities and interdependencies, anticipate bottlenecks, remove barriers to progress, and develop contingency plans.
  • Lead, motivate, and direct matrixed teams to ensure project goals are met.
  • Anticipate barriers, establish risk mitigation strategies, and own program financials, including forecasting and budget tracking.
  • Partner with Finance to ensure budget accuracy, payment tracking, forecast management, and financial reporting.
  • Serve as a business lead with CROs, CDMOs, consultants, and other development vendors.
  • Develop and manage scopes of work, monitor deliverables, approve invoices, and track vendor budgets against plan.

Mandatory Requirements
  • Bachelor’s degree a relevant scientific, engineering, or business discipline
  • 10+ years of Program and Project Management experience
  • Must have experience in managing vendors in an outsourced model
  • Must have clinical trial budgets experience
  • Must have early phase I/II experience
Nice to Have
  • Project Management Professional (PMP) or Program Management Professional (PgMP) certifications preferred
  • Experience in Metabolic Bone Disease
Term & Start
  • Perm
  • September 2026 start date
  • Full time
  • Must be local to Boston, MA
  • Salary up to $250,000 plus bonus and equity options
  • Benefits included (Medical, Dental, Vision, 401k)

 
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