- Location: Massachusetts, United States
- Type: Contract
- Job ID: 10656
- Work Setting: On-Site
- Posted: October 2, 2026
- Closing Date: April 26, 2027
- Tax Status: W2
R&D Scientist
6-month Contract
Onsite in Cambridge, MA
Must be able to work on a W2
Overview:
This role offers an exciting opportunity to lead process development efforts, scale-up activities, and technical transfers in a fast-growing biotech environment. You'll work closely with cross-functional teams, apply your scientific expertise to develop new purification technologies, and help translate laboratory insights into manufacturing success. Your contributions will play a key part in advancing therapies from concept to clinic and beyond, impacting patient outcomes worldwide.
Key Responsibilities:
6-month Contract
Onsite in Cambridge, MA
Must be able to work on a W2
Overview:
This role offers an exciting opportunity to lead process development efforts, scale-up activities, and technical transfers in a fast-growing biotech environment. You'll work closely with cross-functional teams, apply your scientific expertise to develop new purification technologies, and help translate laboratory insights into manufacturing success. Your contributions will play a key part in advancing therapies from concept to clinic and beyond, impacting patient outcomes worldwide.
Key Responsibilities:
- Develop, optimize, and characterize purification processes for oligonucleotides and peptides, including chromatography, ultrafiltration, and chemical modifications
- Investigate and implement innovative purification technologies to improve purity, robustness, and productivity
- Collaborate across research, manufacturing, and technical transfer teams to enhance process understanding and facilitate smooth transitions to production
- Document work thoroughly in development reports, lead pilot-scale activities, and support technology transfer into GMP facilities
- Participate in preparing regulatory documentation, including IND sections, and support troubleshooting and process validation efforts
- Mentor and train junior team members, and lead small projects to improve process efficiency and quality
- Bachelor’s degree in Biochemistry, Chemical Engineering, Chemistry, or related life sciences with 2–4 years of industry experience, or a Master’s degree with 0–2 years in industry
- Hands-on experience with chromatography (ion exchange, hydrophobic interaction, reversed-phase) and ultrafiltration/diafiltration processes
- Knowledge of protein, peptide, or DNA/RNA purification techniques, including analysis via HPLC and UV/Vis spectroscopy
- Familiarity with AKTA systems, Unicorn software, and statistical experimental design (DoE)
- Experience with process characterization and robustness studies
- Exposure to chemical cleavage, conjugation, or hybridization steps
- Experience in process scale-up and tech transfer in a GMP setting
- Familiarity with regulatory documentation for IND submissions