Director of Clinical Pharmacology & DMPK

Consultant, Director / Senior Director of Clinical Pharmacology, Biopharma

Summary
Our client, a fast‑growing biopharmaceutical company focused on immunology, has engaged GForce Life Sciences to provide a Director / Senior Director of Clinical Pharmacology. This position will report to Clinical Pharmacology leadership within the Clinical Development organization. This individual will be responsible for providing hands‑on clinical pharmacology and quantitative pharmacology support across early clinical development programs. This position requires the ability to independently design, execute, and interpret model‑informed analyses to support first‑in‑human studies and early clinical decision‑making.

This position will be supporting multiple active development programs, including late‑stage assets, upcoming regulatory filings, and advancement of new small‑molecule compounds into Phase 1 clinical studies. Will interact with cross‑functional team members across Clinical Development, DMPK, Preclinical Research, and Regulatory.

Duties / Expectations of Role
• Support Phase 1 and first‑in‑human clinical studies, including dose selection
• Perform model‑informed drug development and quantitative analyses
• Conduct translational PK/PD modeling from preclinical to clinical
• Support drug‑drug interaction (DDI), MAT, and QTc cardiac safety assessments
• Contribute to renal and hepatic impairment study strategy and interpretation
• Interface with DMPK and preclinical teams to inform clinical development decisions

Mandatory Requirements
• Scientific degree (Bachelor’s, Master’s, or PhD acceptable)
• 6–8+ years industry experience in Clinical Pharmacology, DMPK, or Quantitative Pharmacology
• First‑in‑human clinical development experience
• Hands‑on experience with modeling tools such as GastroPlus, Simcyp (or similar), Phoenix, NONMEM, R, or Python
• Small‑molecule drug development experience

Nice to Have
• Immunology therapeutic area experience
• Experience working as a senior‑level remote consultant

Term & Start
• 6‑month contract with strong possibility of extension
• Start ASAP
• Full‑time (40 hours/week)
• Possibility of extension or long‑term role
• Remote or hybrid; Bay Area preferred with 2–3 days onsite if local
• Travel: Limited, as needed for key meetings
• Benefits included (Medical, Dental, Vision, 401k)
• Vaccine required: N/A
• Interview process: Resume review, phone interview with hiring manager, followed by panel interview
• Pay rate: starting at $90/hr